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JOINT WEBSITE OF THE HONG KONG THORACIC SOCIETY AND THE CHEST DELEGATION HONG KONG AND MACAU
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2009

2009 Jun - Prevalence of undiagnosed Obstructive Sleep Apnoea in Chinese patients with ST-segment elevation Myocardial Infarction

Dr. Cheung Chun Yu Henry, Department of Medicine, Pamela Youde Nethersole Eastern Hospital

Background:
Obstructive sleep apnoea (OSA) was associated with coronary artery disease (CAD). Outcomes of CAD were worse in those with OSA and treatment of OSA improved the outcomes.

Objectives:
The primary objective of this study was to evaluate the prevalence of un-diagnosed OSA in Chinese patients with ST-segment elevation myocardial infarction (STEMI). The secondary objective was to determine the clinical characteristics that were associated with a respiratory disturbance index (RDI) ≥10.

Methods:
A prospective cohort study was performed at a major public-funded hospital in Hong Kong. Polysomnographies were performed in Chinese STEMI patients in stable conditions. Prevalence of undiagnosed sleep apnoea was determined. Clinical characteristics between patient groups with a RDI <10 or ≥10 were compared.

Results:
Clinical characteristics and polysomnography results of 73 patients were analyzed. The prevalence of undiagnosed OSA was 83.6%. In univariate analysis, habitual snoring, no. of diseased vessel(s), male gender and body weight were significantly associated with a RDI ≥10. Only habitual snoring and no. of diseased vessel(s) were independently associated with a RDI ≥10 after multivariate analysis.

Conclusion:
Chinese STEMI patients had a very high prevalence of un-diagnosed OSA. Habitual snoring and a greater number of diseased vessel(s) were independently associated with a RDI ≥10. It is worthwhile to consider screening for OSA in Chinese STEMI patients, especially in those with habitual snoring and a greater number of diseased vessel(s).

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