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JOINT WEBSITE OF THE HONG KONG THORACIC SOCIETY AND THE CHEST DELEGATION HONG KONG AND MACAU
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2007

2007 Systemic review of cardiovascular disease in patients with Obstructive Sleep Apnoea Syndrome and Role of CPAP use

Dr Lau Chu Leuk
Department of Medicine, Tuen Mun Hospital

Obstructive sleep apnoea syndrome (OSAS) is a common disorder with a reported prevalence of 2-4% of adult population in Hong Kong. Besides symptoms of excessive daytime sleepiness and snoring, the condition is also associated with cardiovascular morbidity. Continuous positive airway pressure (CPAP) machine is the main treatment and has few adverse effects. Treated obstructive sleep apnoea is associated with improved quality of life and mood, and decreases risk for car accidents. Role of CPAP use in OSAS patients with hypertension was regarded as adjunctive in the latest guideline. However, role of CPAP use in OSAS patients with other cardiovascular disease was not mentioned. This review is to evaluate the cardiovascular outcome studies of CPAP use in OSAS patients and the implication for clinical practice. Recent study suggested treatment with CPAP may improve cardiovascular outcome but randomized controlled trial is still lacking. More randomized controlled studies are needed to explore this notion. OSAS being an independent risk factor for cardiovascular morbidity, screening for other cardiovascular risk factors in OSAS patients is suggested

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