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New England Journal of Medicine

2018 Sep 13 - Aspirin-Exacerbated Respiratory Disease

Andrew A. White, M.D., and Donald D. Stevenson, M.D.

N Engl J Med 2018; 379:1060-1070


About 7% of patients with asthma have mucosal swelling, nasal polyps, and worsening of asthma in response to aspirin and other COX-1 inhibitors. Symptoms may be managed with glucocorticoids, antihistamines, and aspirin desensitization.


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